For example, unexplained weight loss combined with persistent changes in bowel habits or blood in the stool should not simply be attributed to getting older or having a stressful period.
The CDC and NCI both include unexplained weight loss among possible signs associated with colorectal or colon cancer. Centers for Disease Control+1
## 5\. Unusual or Persistent Fatigue
Feeling tired after a poor night’s sleep or a demanding day is normal.
Persistent fatigue is different.
Colon cancer can sometimes be associated with anemia, which means having a lower-than-normal level of healthy red blood cells or hemoglobin. Blood loss from the digestive tract can contribute to iron-deficiency anemia, and a person may not always see obvious blood in their stool.
As a result, fatigue may sometimes be one of the less obvious clues that something needs to be investigated.
You might notice that everyday activities require more effort than before, that you feel exhausted despite getting adequate rest, or that your energy has declined for no obvious reason.
